Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants.
George W Carnell,
Martina Billmeier,
Sneha Vishwanath,
Maria Suau Sans,
Hannah Wein,
Charlotte L George,
Patrick Neckermann,
Joanne Marie M Del Rosario,
Alexander T Sampson,
Sebastian Einhauser,
Ernest T Aguinam,
Matteo Ferrari,
Paul Tonks,
Angalee Nadesalingam,
Anja Schütz,
Chloe Qingzhou Huang,
David A Wells,
Minna Paloniemi,
Ingo Jordan,
Diego Cantoni,
David Peterhoff,
Benedikt Asbach,
Volker Sandig,
Nigel Temperton,
Rebecca Kinsley,
Ralf Wagner,
Jonathan L Heeney
Apr 12, 2023
The accelerated development of the first generation COVID-19 vaccines has saved millions of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The most successful vaccine candidates have used the...